1-Boc-2-Piperazinecarboxylic acid methyl ester

1-Boc-2-Piperazinecarboxylic acid methyl ester - Names and Identifiers

Name	N-Boc-piperazine-2-carboxylic acid methyl ester
Synonyms	Piperazine-1,2-dicarb Methyl 1-Boc-2-piperazinecarboxylate METHYL 1-BOC-PIPERAZINE-2-CARBOXYLATE 1-Boc-piperazine-2-carboxylic acid methyl ester N-Boc-piperazine-2-carboxylic acid methyl ester 1-N-BOC-2-PIPERAZINECARBOXYLIC ACID METHYL ESTER N-1-BOC-2-PIPERAZINECARBOXYLIC ACID METHYL ESTER 1-Boc-2-Piperazinecarboxylic acid methyl ester 1-N-BOC-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER 1-tert-butyl 2-methyl piperazine-1,2-dicarboxylate 1-N-BOC-piperazine-2-carboxylic acid Methyl ester-HCl 1,2-Piperazinedicarboxylic acid, 1-(1,1-diMethylethyl) 2-Methyl ester
CAS	129799-15-1
InChI	InChI=1/C11H20N2O4/c1-11(2,3)17-10(15)13-6-5-12-7-8(13)9(14)16-4/h8,12H,5-7H2,1-4H3

1-Boc-2-Piperazinecarboxylic acid methyl ester - Physico-chemical Properties

Molecular Formula	C11H20N2O4
Molar Mass	244.29
Density	1.118g/ml
Boling Point	321.3±37.0 °C(Predicted)
Flash Point	148.1°C
Vapor Presure	0.000301mmHg at 25°C
pKa	7.25±0.40(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.471
MDL	MFCD01861779

1-Boc-2-Piperazinecarboxylic acid methyl ester - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

1-Boc-2-Piperazinecarboxylic acid methyl ester - Introduction

Methyl N-1-Boc-2-piperazine formate is an organic compound with the following properties:

1. Appearance and properties: N-1-Boc-2-piperazine methyl formate is generally colorless to yellowish liquid.
2. solubility: can be dissolved in some organic solvents (such as ethanol, formate), but the solubility in water is low.

The main uses of N-1-Boc-2-piperazinecarboxylic acid methyl ester include:

1. Organic synthesis: It is often used as a protecting group or starting material in organic synthesis for the synthesis of other organic compounds.
2. Pharmaceutical field: N-1-Boc-2-piperazinecarboxylic acid methyl ester can be used as an intermediate in the synthesis of some drugs.

A common method for preparing N-1-Boc-2-piperazine methyl formate is through the reaction of piperazine and methyl formate. The reaction conditions are generally room temperature and carried out under basic conditions.

When using N-1-Boc-2-piperazinecarboxylic acid methyl ester, pay attention to its safety information:

1. toxicity: N-1-Boc-2-piperazine formate methyl ester may be toxic to the human body, contact to avoid skin contact, inhalation or ingestion.
2. Fire hazard: N-1-Boc-2-piperazine methyl formate is flammable and should be avoided in contact with fire sources.
3. Storage and handling: N-1-Boc-2-piperazinecarboxylic acid methyl ester should be stored in a closed container, away from fire and oxidant. Wear suitable personal protective equipment such as gloves and goggles when used. Waste items are to be disposed of in accordance with relevant regulations.
4. Others: When using or handling N-1-Boc-2-piperazine methyl formate, the laboratory safety operating procedures should be followed, and the oxygen concentration and temperature in the laboratory environment should be strictly controlled.

Last Update：2024-04-09 21:21:28